William L. Jorgensen, Ph.D.

William L. Jorgensen, Ph.D.

Sterling Professor of Chemistry, Yale University

Bill Jorgensen is a graduate of Princeton and Harvard, spent 15 years on the faculty at Purdue, and in 1990 moved to Yale, where he is a Sterling Professor and Director of the Division of Physical Sciences and Engineering. Bill's research has combined quantum, statistical, and molecular mechanics to study chemistry in solution. He has been a leader in computational studies of organic and enzymatic reactions in solution, molecular recognition, and protein-ligand binding. His OPLS force fields and TIPnP water models are widely used. Bill’s research group is also actively engaged in de novo drug design and synthesis, particularly for anti-infective, anti-proliferative, and anti-inflammatory agents. Among honors, Bill has received an ACS Cope Scholar Award, the ACS Award for Computers in Chemical and Pharmaceutical Research, the ACS Hildebrand Award, AAAS and ACS Fellowships, the ISQBP Award in Computational Biology, the PSJ Sato International Award, and memberships in the International Academy of Quantum Molecular Science, the American Academy of Arts & Sciences, and the National Academy of Sciences. He is a founder of Rib-X Pharmaceuticals and Editor of two ACS journals, Journal of Chemical Information and Modeling and the Journal of Chemical Theory and Computation.